eyestrain

from WordNet (r) 3.0 (2006)

eyestrain
    n 1: a tiredness of the eyes caused by prolonged close work by a
         person with an uncorrected vision problem [syn:
         {eyestrain}, {asthenopia}]

from Moby Thesaurus II by Grady Ward, 1.0

23 Moby Thesaurus words for "eyestrain":
      brain fag, debilitation, debility, enervation, enfeeblement,
      faintness, fatigue, goneness, heart strain, jadedness, languor,
      lassitude, mental fatigue, mental strain, overstrain,
      overtiredness, sleepiness, stance fatigue, strain, tiredness,
      weakness, wearifulness, weariness