epilepsia major n 1: epilepsy in which the attacks involve loss of consciousness and tonic spasms of the musculature followed by generalized jerking [syn: {grand mal epilepsy}, {grand mal}, {generalized epilepsy}, {epilepsia major}] 2: a seizure during which the patient becomes unconscious and has convulsions over the entire body [syn: {grand mal}, {generalized seizure}, {epilepsia major}]