nystatin \nystatin\ n. [From NY state + -in, due to its discovery in New York State.] An antifungal antibiotic, extracted from fermentation broths of the soil actinomycete {Streptomyces noursei} and other actinomycetes; called also {fungicidin}. It is a polyene macrolide antibiotic, and consists of several related components. Component nystatin A1 has formula {C47H75NO17}. [WordNet 1.5]