Digitalis purpurea
from
The Collaborative International Dictionary of English v.0.48
Foxglove \Fox"glove`\, n. [AS. foxes-gl[=o]fa,
foxes-cl[=o]fa,foxes-clife.] (Bot.)
Any plant of the genus {Digitalis}. The common English
foxglove ({Digitalis purpurea}) is a handsome perennial or
biennial plant, whose leaves are used as a powerful medicine,
both as a sedative and diuretic. See {Digitalis}.
[1913 Webster]
Pan through the pastures oftentimes hath run
To pluck the speckled foxgloves from their stem. --W.
Browne.
[1913 Webster]
from
The Collaborative International Dictionary of English v.0.48
digitalin \dig"i*ta`lin\, n. [Cf. F. digitaline.]
(a) (Medicine, Pharmacy) Any one of several extracts of
foxglove ({Digitalis}), as the "French extract," the
"German extract," etc., which differ among themselves
in composition and properties. Both {Digitalis lanata}
and {Digitalis purpurea} have been used to prepare
such extracts.
(b) (Chem.) the distinctive chemical substance, a steroid
glycoside, which is the essential ingredient of the
extracts of foxglove. It is a white, crystalline
substance ({C36H56O14}), and is a 3-substituted
diglucoside of a steroid. It is a powerful cardiac
stimulant and is used as a cardiotonic for treatment
of certain heart conditions, such as congestive heart
failure. Chemically it is
(3[beta],5[beta],16[beta])-3-[6-Deoxy-4-O-[beta]-D-glucopyranosyl-3-O-methyl-[beta]-D-galactopyranosyl)oxy]-14,16-dihyroxy-card-20
(22)-enolide. The related compounds {digitoxin} and
{digoxin} are also extracted from the foxglove. The
class of steroid glycosides having cardiotonic
properties are refered to as the cardiac glycosides.
--MI11
Syn: digitalinum verum, Diginorgin, Schmiedeberg's digitalin,
digitalis, digitalis glycoside. [1913 Webster +PJC]
from
The Collaborative International Dictionary of English v.0.48
digitoxin \dig`i*tox"in\ (d[i^]j`[i^]*t[o^]k"s[i^]n), n. (Chem.)
A steroid glycoside, one of the cardiotonic chemical
substances which is extracted from the foxglove. It is a
white, crystalline substance ({C41H64O13}), and is a
3-substituted triglucoside of a steroid, related structurally
to digitalin and digoxin. It is used as a cardiotonic for
treatment of certain heart conditions, such as congestive
heart failure. Chemically it is
(3[beta],5[beta])-3-[(O-2,6-Dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-O-2,6-dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-2,
6-dideoxy-[beta]-D-ribo-hexopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide.
The related compounds {digitalin} and {digoxin} are also
extracted from the foxglove ({Digitalis lanata} and
{Digitalis purpurea}). The class of steroid glycosides having
cardiotonic properties are refered to as the cardiac
glycoside group. --MI11
[PJC]
from
The Collaborative International Dictionary of English v.0.48
digoxin \di*gox"in\, n. (Chem.)
a steroid glycoside, one of the cardiotonic chemical
substances which is extracted from the foxglove. It is a
white, crystalline substance ({C41H64O14}), and is a
3-substituted triglucoside of a steroid, related structurally
to digitalin and digitoxin. It is used as a cardiotonic for
treatment of certain heart conditions, such as congestive
heart failure. Chemically it is
(3[beta],5[beta],12[beta])-3-[(O-2,6-Dideoxy-[beta]-D-ribo-hexopyranosyl-(1->4)-O-2,6-dideoxy-[beta]-D-ribo-hexopyranosyl-(1->4)-2
, 6-dideoxy-[beta]-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-card-20(22)-enolide.
The related compounds {digitalin} and {digoxin} are also
extracted from the foxglove ({Digitalis lanata} and
{Digitalis purpurea}). The class of steroid glycosides having
cardiotonic properties are refered to as the cardiac
glycosides. --MI11
[PJC]
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