Tuscola -- U.S. County in Michigan Population (2000): 58266 Housing Units (2000): 23378 Land area (2000): 812.428731 sq. miles (2104.180663 sq. km) Water area (2000): 101.393247 sq. miles (262.607294 sq. km) Total area (2000): 913.821978 sq. miles (2366.787957 sq. km) Located within: Michigan (MI), FIPS 26 Location: 43.463550 N, 83.434400 W Headwords: Tuscola Tuscola, MI Tuscola County Tuscola County, MI