Tetramethylene \Tet`ra*meth"yl*ene\, n. [Tetra- + methylene.] (Chem.) (a) A hypothetical hydrocarbon, {C4H8}, analogous to trimethylene, and regarded as the base of well-known series or derivatives. (b) Sometimes, an isomeric radical used to designate certain compounds which are really related to butylene. [1913 Webster]