Spartanburg -- U.S. County in South Carolina Population (2000): 253791 Housing Units (2000): 106986 Land area (2000): 810.925232 sq. miles (2100.286619 sq. km) Water area (2000): 8.218413 sq. miles (21.285592 sq. km) Total area (2000): 819.143645 sq. miles (2121.572211 sq. km) Located within: South Carolina (SC), FIPS 45 Location: 34.962187 N, 82.004019 W Headwords: Spartanburg Spartanburg, SC Spartanburg County Spartanburg County, SC