Slough \Slough\, v. i. [imp. & p. p. {Sloughed}; p. pr. & vb. n. {Sloughing}.] (Med.) To form a slough; to separate in the form of dead matter from the living tissues; -- often used with off, or away; as, a sloughing ulcer; the dead tissues slough off slowly. [1913 Webster]