Roanoke -- U.S. County in Virginia Population (2000): 85778 Housing Units (2000): 36121 Land area (2000): 250.865591 sq. miles (649.738871 sq. km) Water area (2000): 0.178138 sq. miles (0.461376 sq. km) Total area (2000): 251.043729 sq. miles (650.200247 sq. km) Located within: Virginia (VA), FIPS 51 Location: 37.250378 N, 80.000204 W Headwords: Roanoke Roanoke, VA Roanoke County Roanoke County, VA