prion n 1: (microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system
Prion \Pri"on\ (pr[=e]"[o^]n), n. any of several types of protein particle lacking nucleic acid, believed to be the cause of certain slow-developing infectious diseases such as scapie in sheep, and Creutzfeldt-Jakob disease and Kuru in humans. [informal] [PJC]