Potosi, MO -- U.S. city in Missouri Population (2000): 2662 Housing Units (2000): 1211 Land area (2000): 2.184009 sq. miles (5.656558 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 2.184009 sq. miles (5.656558 sq. km) FIPS code: 59330 Located within: Missouri (MO), FIPS 29 Location: 37.937881 N, 90.781932 W ZIP Codes (1990): 63664 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Potosi, MO Potosi