Port Isabel, TX -- U.S. city in Texas Population (2000): 4865 Housing Units (2000): 2055 Land area (2000): 2.195940 sq. miles (5.687458 sq. km) Water area (2000): 0.712543 sq. miles (1.845477 sq. km) Total area (2000): 2.908483 sq. miles (7.532935 sq. km) FIPS code: 58892 Located within: Texas (TX), FIPS 48 Location: 26.073675 N, 97.213234 W ZIP Codes (1990): 78578 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Port Isabel, TX Port Isabel