Pontotoc -- U.S. County in Mississippi Population (2000): 26726 Housing Units (2000): 10816 Land area (2000): 497.351756 sq. miles (1288.135081 sq. km) Water area (2000): 3.643059 sq. miles (9.435479 sq. km) Total area (2000): 500.994815 sq. miles (1297.570560 sq. km) Located within: Mississippi (MS), FIPS 28 Location: 34.247321 N, 89.015613 W Headwords: Pontotoc Pontotoc, MS Pontotoc County Pontotoc County, MS