phren- \phren-\, phreno- \phreno-\, phreni- \phreni-\, phrenico- \phrenico-\(fr[e^]n- or fr[=e]n-), n. [Gr. frh`n, freno`s, the midriff, or diaphragm, the heart (as the seat of emotions), the mind.] (Anat.) A combining form meaning, of or pertaining to the diaphragm, the mind, or the brain; frenic. --Stedman. [PJC]