Pathogen \Path"o*gen\, Pathogene \Path"o*gene\, n. [See {Pathogenic}.] (Biol.) Any microorganism which causes disease; a pathogenic organism; an infectious microorganism; a bacterium, virus, or other agent which can cause disease by infection; -- opposed to {zymogene}. The spelling pathogene is now archaic. [1913 Webster + PJC]