Opelousas, LA -- U.S. city in Louisiana Population (2000): 22860 Housing Units (2000): 9783 Land area (2000): 7.055522 sq. miles (18.273717 sq. km) Water area (2000): 0.009990 sq. miles (0.025875 sq. km) Total area (2000): 7.065512 sq. miles (18.299592 sq. km) FIPS code: 58045 Located within: Louisiana (LA), FIPS 22 Location: 30.528183 N, 92.084406 W ZIP Codes (1990): 70570 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Opelousas, LA Opelousas