Opelika, AL -- U.S. city in Alabama Population (2000): 23498 Housing Units (2000): 10281 Land area (2000): 52.772178 sq. miles (136.679307 sq. km) Water area (2000): 0.662879 sq. miles (1.716849 sq. km) Total area (2000): 53.435057 sq. miles (138.396156 sq. km) FIPS code: 57048 Located within: Alabama (AL), FIPS 01 Location: 32.647183 N, 85.389404 W ZIP Codes (1990): 36801 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Opelika, AL Opelika