Lexington -- U.S. County in South Carolina Population (2000): 216014 Housing Units (2000): 90978 Land area (2000): 699.252734 sq. miles (1811.056191 sq. km) Water area (2000): 58.630164 sq. miles (151.851421 sq. km) Total area (2000): 757.882898 sq. miles (1962.907612 sq. km) Located within: South Carolina (SC), FIPS 45 Location: 33.949223 N, 81.232319 W Headwords: Lexington Lexington, SC Lexington County Lexington County, SC