La Crosse -- U.S. County in Wisconsin Population (2000): 107120 Housing Units (2000): 43479 Land area (2000): 452.740754 sq. miles (1172.593119 sq. km) Water area (2000): 27.175180 sq. miles (70.383389 sq. km) Total area (2000): 479.915934 sq. miles (1242.976508 sq. km) Located within: Wisconsin (WI), FIPS 55 Location: 43.859415 N, 91.189127 W Headwords: La Crosse La Crosse, WI La Crosse County La Crosse County, WI