Isoprene \I"so*prene\, n. [Etymol. uncertain.] (Chem.) An oily, volatile unsaturated hydrocarbon ({C5H8}), obtained by the distillation of caoutchouc or gutta-percha, and used to make synthetic rubber by polymerization. In organic chemistry, it is viewed conceptually as the building block of the terpene series of hydrocarbons. [1913 Webster +PJC]