Isabela -- U.S. Municipio in Puerto Rico Population (2000): 44444 Housing Units (2000): 17166 Land area (2000): 55.364023 sq. miles (143.392155 sq. km) Water area (2000): 36.584999 sq. miles (94.754708 sq. km) Total area (2000): 91.949022 sq. miles (238.146863 sq. km) Located within: Puerto Rico (PR), FIPS 72 Location: 18.467536 N, 67.012939 W Headwords: Isabela Isabela, PR Isabela Municipio Isabela Municipio, PR