downs syndrome

from The Collaborative International Dictionary of English v.0.48

Down syndrome \Down" syn`drome\, Down's syndrome \Down's"
syn`drome\, n. (Med.)
   A congenital disorder caused by an extra chromosome 21 in
   some or all cells. It causes a variable number and degree of
   abnormalities, including retarded growth, mental retardation,
   a short nose, prominent epicanthic folds on the eyelids, a
   protruding lower lip, and other physical features having
   varying degrees of deviation from the normal. Called also
   {mongolism}, {trisomy-21} and {trisomy 21 syndrome}.
   [PJC]