DeSoto, TX -- U.S. city in Texas Population (2000): 37646 Housing Units (2000): 14069 Land area (2000): 21.579750 sq. miles (55.891294 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 21.579750 sq. miles (55.891294 sq. km) FIPS code: 20092 Located within: Texas (TX), FIPS 48 Location: 32.599286 N, 96.858828 W ZIP Codes (1990): Note: some ZIP codes may be omitted esp. for suburbs. Headwords: DeSoto, TX DeSoto