Depurate \Dep"u*rate\, v. t. [imp. & p. p. {Depurated}; p. pr. & vb. n. {Depurating}.] To free from impurities, heterogeneous matter, or feculence; to purify; to cleanse. [1913 Webster] To depurate the mass of blood. --Boyle. [1913 Webster]