Defiance -- U.S. County in Ohio Population (2000): 39500 Housing Units (2000): 16040 Land area (2000): 411.158299 sq. miles (1064.895060 sq. km) Water area (2000): 3.027456 sq. miles (7.841076 sq. km) Total area (2000): 414.185755 sq. miles (1072.736136 sq. km) Located within: Ohio (OH), FIPS 39 Location: 41.304320 N, 84.462745 W Headwords: Defiance Defiance, OH Defiance County Defiance County, OH