Defiance, IA -- U.S. city in Iowa Population (2000): 346 Housing Units (2000): 131 Land area (2000): 0.398193 sq. miles (1.031314 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 0.398193 sq. miles (1.031314 sq. km) FIPS code: 19585 Located within: Iowa (IA), FIPS 19 Location: 41.824740 N, 95.342056 W ZIP Codes (1990): Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Defiance, IA Defiance