De Soto, KS -- U.S. city in Kansas Population (2000): 4561 Housing Units (2000): 1730 Land area (2000): 11.317115 sq. miles (29.311191 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 11.317115 sq. miles (29.311191 sq. km) FIPS code: 17850 Located within: Kansas (KS), FIPS 20 Location: 38.965081 N, 94.962285 W ZIP Codes (1990): 66018 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: De Soto, KS De Soto