De Soto, IA -- U.S. city in Iowa Population (2000): 1009 Housing Units (2000): 401 Land area (2000): 1.480858 sq. miles (3.835404 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 1.480858 sq. miles (3.835404 sq. km) FIPS code: 21045 Located within: Iowa (IA), FIPS 19 Location: 41.531060 N, 94.008423 W ZIP Codes (1990): 50069 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: De Soto, IA De Soto