Colleton -- U.S. County in South Carolina Population (2000): 38264 Housing Units (2000): 18129 Land area (2000): 1056.356209 sq. miles (2735.949905 sq. km) Water area (2000): 76.855534 sq. miles (199.054910 sq. km) Total area (2000): 1133.211743 sq. miles (2935.004815 sq. km) Located within: South Carolina (SC), FIPS 45 Location: 32.888847 N, 80.672583 W Headwords: Colleton Colleton, SC Colleton County Colleton County, SC