Cherokee -- U.S. County in Alabama Population (2000): 23988 Housing Units (2000): 14025 Land area (2000): 553.120811 sq. miles (1432.576264 sq. km) Water area (2000): 46.830697 sq. miles (121.290944 sq. km) Total area (2000): 599.951508 sq. miles (1553.867208 sq. km) Located within: Alabama (AL), FIPS 01 Location: 34.184158 N, 85.621930 W Headwords: Cherokee Cherokee, AL Cherokee County Cherokee County, AL