Carlisle -- U.S. County in Kentucky Population (2000): 5351 Housing Units (2000): 2490 Land area (2000): 192.486176 sq. miles (498.536885 sq. km) Water area (2000): 6.537455 sq. miles (16.931931 sq. km) Total area (2000): 199.023631 sq. miles (515.468816 sq. km) Located within: Kentucky (KY), FIPS 21 Location: 36.851769 N, 88.952666 W Headwords: Carlisle Carlisle, KY Carlisle County Carlisle County, KY