Cairo, MO -- U.S. village in Missouri Population (2000): 293 Housing Units (2000): 127 Land area (2000): 0.268029 sq. miles (0.694193 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 0.268029 sq. miles (0.694193 sq. km) FIPS code: 10360 Located within: Missouri (MO), FIPS 29 Location: 39.512027 N, 92.440887 W ZIP Codes (1990): 65239 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Cairo, MO Cairo