Codeine \Co"deine\ (k[=o]"d[=e]n or k[-o]*d[=e]"[i^]n), n. [Gr. kw`deia poppy head: cf. F. cod['e]ine.] (Chem.) One of the opium alkaloids; a white crystalline substance, {C18H21NO3}, similar to and regarded as a derivative of morphine, but much feebler in its action; -- called also {codeia}. [1913 Webster]