Buffalo -- U.S. County in South Dakota Population (2000): 2032 Housing Units (2000): 602 Land area (2000): 470.593646 sq. miles (1218.831895 sq. km) Water area (2000): 16.834714 sq. miles (43.601707 sq. km) Total area (2000): 487.428360 sq. miles (1262.433602 sq. km) Located within: South Dakota (SD), FIPS 46 Location: 44.047466 N, 99.271746 W Headwords: Buffalo Buffalo, SD Buffalo County Buffalo County, SD