Brookline, MO -- U.S. village in Missouri Population (2000): 326 Housing Units (2000): 155 Land area (2000): 4.008532 sq. miles (10.382049 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 4.008532 sq. miles (10.382049 sq. km) FIPS code: 08722 Located within: Missouri (MO), FIPS 29 Location: 37.179117 N, 93.417279 W ZIP Codes (1990): Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Brookline, MO Brookline