atheroma n 1: a fatty deposit in the intima (inner lining) of an artery; can obstruct blood flow
Atheroma \Ath`e*ro"ma\, n. [L., fr. Gr. ?, ?, fr. ? gr?ats, meal.] (Med.) (a) An encysted tumor containing curdy matter. (b) A disease characterized by thickening and fatty degeneration of the inner coat of the arteries. [1913 Webster]