Adrian, MI -- U.S. city in Michigan Population (2000): 21574 Housing Units (2000): 8498 Land area (2000): 7.135402 sq. miles (18.480606 sq. km) Water area (2000): 0.126808 sq. miles (0.328430 sq. km) Total area (2000): 7.262210 sq. miles (18.809036 sq. km) FIPS code: 00440 Located within: Michigan (MI), FIPS 26 Location: 41.896526 N, 84.037827 W ZIP Codes (1990): 49221 Note: some ZIP codes may be omitted esp. for suburbs. Headwords: Adrian, MI Adrian