TSR

from The Free On-line Dictionary of Computing (8 July 2008)
Terminate and Stay Resident
TSR

   (TSR) A type of {DOS} utility which, once loaded, stays in
   memory and can be reactivated by pressing a certain
   combination of keys.
    
from V.E.R.A. -- Virtual Entity of Relevant Acronyms (June 2006)
TSR
       Terminate and Stay Resident
       
    

[email protected]