karyoplasm \kar`y*o*plas"m\ (k[a^]r`[i^]*[-o]*pl[a^]z"'m), karyoplasma \kar`y*o*plas"ma\(k[a^]r`[i^]*[-o]*pl[a^]z"m[.a]), n. [NL., fr. Gr. ka`ryon a nut + pla`sma a thing molded.] (Biol.) The protoplasmic substance of the nucleus of a cell; nucleoplasm; -- in opposition to {cytoplasm}, the protoplasm of the cell. [1913 Webster]