Des Moines -- U.S. County in Iowa Population (2000): 42351 Housing Units (2000): 18643 Land area (2000): 416.148452 sq. miles (1077.819498 sq. km) Water area (2000): 13.649589 sq. miles (35.352273 sq. km) Total area (2000): 429.798041 sq. miles (1113.171771 sq. km) Located within: Iowa (IA), FIPS 19 Location: 40.854437 N, 91.156013 W Headwords: Des Moines Des Moines, IA Des Moines County Des Moines County, IA