63845 -- U.S. ZIP code Municipality (1990): EAST PRAIRIE, Missouri All ZIPs for this municipality (1990): 63845 Population (2000): 5853 Housing Units (2000): 2548 Land area (2000): 246.584806 sq. miles (638.651689 sq. km) Water area (2000): 1.175901 sq. miles (3.045569 sq. km) Total area (2000): 247.760707 sq. miles (641.697258 sq. km) Located within: Missouri (MO) Location: 36.744320 N, 89.361423 W