63301 -- U.S. ZIP code Municipality (1990): SAINT CHARLES, Missouri All ZIPs for this municipality (1990): 63301 63303 63304 Population (2000): 46052 Housing Units (2000): 19269 Land area (2000): 85.725842 sq. miles (222.028901 sq. km) Water area (2000): 0.479206 sq. miles (1.241138 sq. km) Total area (2000): 86.205048 sq. miles (223.270039 sq. km) Located within: Missouri (MO) Location: 38.808583 N, 90.506878 W