33543 -- U.S. ZIP code Municipality (1990): WESLEY CHAPEL, Florida All ZIPs for this municipality (1990): 33543 Population (2000): 12019 Housing Units (2000): 5260 Land area (2000): 32.469053 sq. miles (84.094457 sq. km) Water area (2000): 0.105392 sq. miles (0.272964 sq. km) Total area (2000): 32.574445 sq. miles (84.367421 sq. km) Located within: Florida (FL) Location: 28.187356 N, 82.316019 W