unease

from WordNet (r) 3.0 (2006)

unease
    n 1: physical discomfort (as mild sickness or depression) [syn:
         {malaise}, {unease}, {uneasiness}]
    2: the trait of seeming ill at ease [syn: {disquiet}, {unease},
       {uneasiness}]

from The Collaborative International Dictionary of English v.0.48

Unease \Un*ease"\, n.
   Want of ease; uneasiness. [Obs.]
   [1913 Webster]