botheration

from WordNet (r) 3.0 (2006)

botheration
    n 1: the psychological state of being irritated or annoyed [syn:
         {irritation}, {annoyance}, {vexation}, {botheration}]
    2: something or someone that causes trouble; a source of
       unhappiness; "washing dishes was a nuisance before we got a
       dish washer"; "a bit of a bother"; "he's not a friend, he's
       an infliction" [syn: {annoyance}, {bother}, {botheration},
       {pain}, {infliction}, {pain in the neck}, {pain in the ass}]

from The Collaborative International Dictionary of English v.0.48

Botheration \Both`er*a"tion\, n.
   The act of bothering, or state of being bothered; cause of
   trouble; perplexity; annoyance; vexation. [Colloq.]
   [1913 Webster]